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PSNet: Patient Safety Network
Journal Article

Effect of behavioral interventions on inappropriate antibiotic prescribing among primary care practices: a randomized clinical trial.

Meeker D, Linder JA, Fox CR, et al. JAMA. 2016;315:562-70.

In this cluster randomized trial among 47 primary care practices, prompting clinicians to enter justifications for prescribing antibiotics in patients with antibiotic-inappropriate diagnoses or providing peer comparisons through emails decreased mean antibiotic prescribing rates compared to controls. Antibiotics are a significant source of medical care overuse and inappropriate prescriptions can lead to avoidable harms.