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From the randomized AMBORA trial to clinical practice: comparison of medication errors in oral antitumor therapy.

Cuba L, Dürr P, Dörje F, et al. From the randomized AMBORA trial to clinical practice: comparison of medication errors in oral antitumor therapy. Clin Pharmacol Ther. 2024;116(1):194-203. doi:10.1002/cpt.3266.

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July 10, 2024
Cuba L, Dürr P, Dörje F, et al. Clin Pharmacol Ther. 2024;116(1):194-203.
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Randomized controlled trials (RCT) are conducted with stringent inclusion criteria and thus may not reflect real-world clinical practice. This study compares the medication error rates of the AMBORA care program implemented in routine clinical care with the rates found during the RCT. Medication errors were significantly more common in the real-world setting, potentially due to more complex oral antitumor therapy combination regimens or higher number of total medications per patient. Other demographics and outcomes (e.g., type of error) were similar in both groups.

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Cuba L, Dürr P, Dörje F, et al. From the randomized AMBORA trial to clinical practice: comparison of medication errors in oral antitumor therapy. Clin Pharmacol Ther. 2024;116(1):194-203. doi:10.1002/cpt.3266.

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