This report summarizes the efforts of a committee of engineers and health care professionals. The group was brought together with a mission to identify engineering tools and technologies that foster improvements in the health care delivery system. The two-part report begins with a detailed discussion of the partnership between engineering and medicine, a framework for a systems approach in health care, the role of engineering tools and information technology, and a strategy to accelerate change. Each section offers specific recommendations. The second part represents the proceedings from workshops with experts in the engineering, health, management, and social science communities.