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Incidence and preventability of adverse drug events among older persons in the ambulatory setting.

Gurwitz JH, Field T, Harrold LR, et al. Incidence and Preventability of Adverse Drug Events Among Older Persons in the Ambulatory Setting. JAMA. 2003;289(9):1107-1116. doi:10.1001/jama.289.9.1107.

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March 6, 2005
Gurwitz JH, Field T, Harrold LR, et al. JAMA. 2003;289(9):1107-1116.

This study analyzed more than 1500 adverse drug events and discovered that nearly 28% were preventable. Investigators studied a large population of Medicare enrollees in a single multispecialty group practice capturing events through a number of strategies that included reports from health care providers, review of hospital discharge summaries and emergency department notes, free-text review of electronic clinic notes, and others. The overall rate of adverse drug events approached 50 per 1000 person-years with the most serious events and preventable events occurring at the time of prescribing and monitoring. The authors present a detailed classification of the drug events along with the most common events and medications implicated. While this study focused on an elderly population, a similar study presented their findings from the ambulatory setting in general.

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Gurwitz JH, Field T, Harrold LR, et al. Incidence and Preventability of Adverse Drug Events Among Older Persons in the Ambulatory Setting. JAMA. 2003;289(9):1107-1116. doi:10.1001/jama.289.9.1107.