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PSNet: Patient Safety Network
Journal Article

Prescription of long-acting opioids and mortality in patients with chronic noncancer pain.

Ray WA, Chung CP, Murray KT, et al. JAMA. 2016;315:2415-23.

Opioid use can increase risk of adverse drug events, including overdoses. In this retrospective study, researchers found that the use of long-acting opioids in patients with chronic noncancer pain was associated with greater risk of mortality when compared with patients using other classes of analgesic medications.