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The MedSafer study-electronic decision support for deprescribing in hospitalized older adults: a cluster randomized clinical trial.
February 2, 2022
McDonald EG, Wu PE, Rashidi B, et al. JAMA Intern Med. 2022;182(3):265-273.
Deprescribing is one intervention to reduce the risk of adverse drug events, particularly in older adults and people taking five or more medications. In this cluster randomized trial, older adults (≥65 years) taking at least five medications at hospital admission were randomly assigned to intervention (personalized reports of deprescribing opportunities) or control. Despite an increase in deprescribing in both groups, there was no difference in adverse drug events or adverse drug withdrawal events.
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