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December 6, 2023 Weekly Issue

PSNet highlights the latest patient safety literature, news, and expert commentary, including Weekly Updates, WebM&M, and Perspectives on Safety. The current issue highlights what's new this week in patient safety literature, news, conferences, reports, and more. Past issues of the PSNet Weekly Update are available to browse. WebM&M presents current and past monthly issues of Cases & Commentaries and Perspectives on Safety.

This Week’s Featured Articles

Blatter C, Osińska M, Simon M, et al. Int J Nurs Stud. 2023;150:104641.
Minimum nurse staffing levels have been promoted by researchers and legislators to reduce adverse events and improve patient safety in both hospitals and nursing homes. While this review of reviews found higher nurse staffing was generally associated with positive outcomes, results varied between staffing groups (e.g., registered nurses compared to licensed vocational/practical nurses or nursing assistants). The authors identified several methodological challenges and described how study design modifications could yield a more robust examination of the causal relationship between staffing and outcomes.
Montalmant KE, Ettinger AK. J Racial Ethn Health Disparities. 2023;Epub Nov 13.
The increased risk of maternal morbidity and mortality among Black women in the United States is a patient safety and public health crisis. This literature review of 42 articles highlights the importance of cultural competence and disparities training for obstetric providers to reduce maternal mortality and morbidity among Black women. The authors also highlight the need for increased awareness regarding the increased risk of cardiovascular diseases among pregnant Black women.
Simon LT, Van Buren T. NEJM Catal Innov Care Deliv. 2023;4.
Achieving zero preventable harm is an ongoing goal for healthcare organizations. This article describes one large, multistate community health system’s experience decreasing serious adverse events through implementation of high-reliability leadership, promoting human error prevention behaviors, and accelerating learning through a structured approach to cause analysis at both the individual and systems levels.
Zhong A, Amat MJ, Anderson TS, et al. JAMA Netw Open. 2023;6:e2343417.
Increased use of telehealth presents both benefits and potential threats to patient safety. In this study of 4,133 patients, researchers found that orders for colonoscopies or cardiac stress tests and dermatology referrals placed during telehealth visits were less likely to be completed within the designated timeframe compared to those ordered during in-person visits (43% vs. 58%). Not completing test or referrals within the recommended timeframe can increase the risk of delayed diagnoses and patient harm.
Bushuven S, Bentele M, Bentele S, et al. J Med Syst. 2023;47:123.
ChatGPT has emerged as a potentially useful tool for clinicians and the public in obtaining heath advice and diagnosis. In this study, six iterations of 22 pediatric emergency vignettes were entered into ChatGPT (total of 132 scenarios) to assess diagnostic accuracy, emergency call advice, and validity of advice given. ChatGPT correctly recommended contacting medical professionals in all cases but only advised calling emergency medical services (EMS) or 911 in 12 of the 22 scenarios. The correct diagnosis was made in 94% of cases, consistent with other research into ChatGPT. Considerably more research is required before ChatGPT could be recommended for diagnostic advice.
Zhong A, Amat MJ, Anderson TS, et al. JAMA Netw Open. 2023;6:e2343417.
Increased use of telehealth presents both benefits and potential threats to patient safety. In this study of 4,133 patients, researchers found that orders for colonoscopies or cardiac stress tests and dermatology referrals placed during telehealth visits were less likely to be completed within the designated timeframe compared to those ordered during in-person visits (43% vs. 58%). Not completing test or referrals within the recommended timeframe can increase the risk of delayed diagnoses and patient harm.
Hibbert PD, Stewart S, Wiles LK, et al. Int J Qual Health Care. 2023;35:1-11.
Quality improvement and patient safety initiatives require incredible human and financial resources, they so must be selected carefully to achieve the greatest return on investment. This article describes important considerations for hospital leaders when selecting and implementing initiatives. Safety culture, policies and procedures, supporting staff, and patient engagement were notable themes. The included "patient safety governance model" provides a framework to develop patient safety policy.
Hattingh HL, Edmunds C, Gillespie BM. J Pharm Policy Pract. 2023;16:127.
Remote or virtual patient care was an increasingly common strategy during the COVID-19 pandemic to keep patients safe and ensure adequate inpatient resources for patients unable to be cared for virtually. In this study, hospital physicians, pharmacists, and nurses described medication challenges associated with patients receiving virtual care (i.e., hospital-level care at home or hotel). Participants described challenges with lack of clarity on who is responsible for the patient's usual home medications, disruptions to typical workflow, and difficulties with transition from inpatient to virtual care.
Etheridge JC, Moyal-Smith R, Yong TT, et al. JAMA Surg. 2024;159:78-86.
Surgical safety checklists have been credited with improving perioperative patient outcomes, but numerous studies have shown implementation to be variable across settings and surgical specialties. This study aimed to redesign and reimplement the surgical safety checklist in two academic hospitals. Item completion and fidelity improved after reimplementation and exploratory analysis suggests improved patient outcomes (e.g., serious complications).
List JM, Russell LE, Hausmann LRM, et al. Jt Comm J Qual Patient Saf. 2024;50:34-40.
Unmet health-related social needs (HRSNs; e.g., housing instability, food insecurity) and healthcare disparities can place patients at increased risk for patient safety incidents and poor outcomes. This article describes how existing Veterans Health Administration (VHA) initiatives to address HRSNs and disparities are being leveraged to address new Joint Commission standards to improve health care equity.
Simon LT, Van Buren T. NEJM Catal Innov Care Deliv. 2023;4.
Achieving zero preventable harm is an ongoing goal for healthcare organizations. This article describes one large, multistate community health system’s experience decreasing serious adverse events through implementation of high-reliability leadership, promoting human error prevention behaviors, and accelerating learning through a structured approach to cause analysis at both the individual and systems levels.
Sittig DF, Yackel EE, Singh H. J Gen Intern Med. 2023;38:940-942.
Large-scale technology modifications can contribute to organizational disfunction. This commentary discusses five approaches to managing disruption associated with electronic health record modernization that establish cultural, functionality, staff, design, and monitoring conditions to reduce stress and the potential for patient harm during technology improvements.
Leon C, Hogan H, Jani YH. BMJ Qual Saf. 2024;33:173-186.
Errors associated with high-risk medications (HRM) like insulin and anticoagulants carry a greater risk for harm. The purpose of this scoping review was to identify measures evaluating the safety of HRM during transitions of care. Measures were mapped to frameworks (e.g., Donabedian) and whether measures were reactive, proactive, or real-time. The authors describe ways technology can improve how the measures are implemented.
Ahmed M, Suhrawardy A, Olszewski A, et al. J Am Acad Orthop Surg. 2024;32:75-82.
Overlapping surgeries, where one attending surgeon supervises two surgeries with noncritical portions occurring simultaneously, are generally considered as safe as non-overlapping surgeries. This review identified 11 studies into safety outcomes of overlapping orthopedic surgeries involving 34,494 overlapping surgeries. Consistent with prior research, although overlapping surgeries tended to have increased surgical times, short-term outcomes were no different than non-overlapping; one study showed increased risk for adverse events at one year. The authors suggest future research into overlapping robotic-assisted surgeries.
Ledger TS, Brooke-Cowden K, Coiera E. J Am Med Inform Assoc. 2023;30:2064-2071.
Computerized provider order entry (CPOE) systems can reduce medication errors by alerting prescribers to a variety of potential adverse events. However, too many alerts may result in alert fatigue. This scoping review identified 16 studies on interventions to reduce alert fatigue. Most interventions focused on drug-drug interactions. A decrease in the quantity and frequency of alerts was seen as a positive outcome, however only four of the studies reported any patient safety outcomes.
Montalmant KE, Ettinger AK. J Racial Ethn Health Disparities. 2023;Epub Nov 13.
The increased risk of maternal morbidity and mortality among Black women in the United States is a patient safety and public health crisis. This literature review of 42 articles highlights the importance of cultural competence and disparities training for obstetric providers to reduce maternal mortality and morbidity among Black women. The authors also highlight the need for increased awareness regarding the increased risk of cardiovascular diseases among pregnant Black women.
Blatter C, Osińska M, Simon M, et al. Int J Nurs Stud. 2023;150:104641.
Minimum nurse staffing levels have been promoted by researchers and legislators to reduce adverse events and improve patient safety in both hospitals and nursing homes. While this review of reviews found higher nurse staffing was generally associated with positive outcomes, results varied between staffing groups (e.g., registered nurses compared to licensed vocational/practical nurses or nursing assistants). The authors identified several methodological challenges and described how study design modifications could yield a more robust examination of the causal relationship between staffing and outcomes.
No results.

Rockville, MD: Agency for Healthcare Research and Quality; 2023-2024. 

The application of evidence in real situations helps to embed innovation across systems and sustain care improvement. This collection of project highlight reports shares descriptions of implementation projects and research funded by AHRQ. The latest report examines the role of teamwork as a component of safety success.
Organizational Policy/Guidelines

Smyrna, GA: Patients for Patient Safety US; December 1, 2023.

Effective measurement has been a long-standing challenge across patient safety efforts to generate data useful across environments to gain overarching understanding of problems and areas to target for improvement. This document outlines a multi-domain series of draft structural measures for use in Centers for Medicare & Medicaid Services (CMS) programs to identify the robustness of organizational factors such as leadership commitment and patient engagement to support safety improvement. Comments can be submitted until December 22, 2023.

This Month’s WebM&Ms

WebM&M Cases
Spotlight Case
Rachel Ann Hight, MD, FACS |
This case describes a 55-year-old woman who sustained critical injuries after a motor vehicle crash and had a lengthy hospitalization. On hospital day 30, a surgeon placed a percutaneous endoscopic gastrostomy (PEG) tube in the intensive care unit (ICU) after computed tomography (CT) scan showed no interposed bowel between the stomach and the anterior abdominal wall.  After the uncomplicated PEG placement, the surgeon cleared the patient’s team to advance tube feeds as tolerated. After several weeks of poorly tolerated tube feedings, the interventional radiology team reviewed a CT scan which had been obtained by another service 6 days after the PEG was placed and noted (for the first time) that the gastrostomy tube traversed the liver. Insufficient communication and fragmented care coordination across care settings contributed to poor management of the malpositioned PEG tube. The commentary underscores the importance of clear documentation of complications, highlights best practices to mitigate risks during patient care transition, and the importance of using multiple communication approaches to ensure appropriate continuity of care.
WebM&M Cases
Christian Bohringer, MBBS, and Sharon Ashley, MD |
A 38-year-old woman with class 3 obesity required removed of a gastric balloon under general anesthesia. She required a relatively large dose of rocuronium for endotracheal intubation, and she was given intravenous sugammadex (200 mg) at the end of the procedure to reverse the neuromuscular block. A quantitative neuromuscular block monitor was not used, but reliance was placed on clinical signs. Shortly after arrival in the post-anesthesia care unit, she couldn’t move or open her eyes and became jittery with low oxygen saturation. Quantitative blockade monitoring revealed a “train of four” (TOF) ratio less than 70%, so she was given another 200 mg of intravenous sugammadex with return of normal motor function.
WebM&M Cases
Luciano Sanchez, PharmD and Patrick Romano, MD, MPH |
An 81-year-old man was admitted to the intensive care unit (ICU) with a gastrointestinal bleed and referred for a diagnostic colonoscopy. The nurse preparing the patient for the colonoscopy mistakenly selected a jug of dialysis liquid rather than a polyethylene glycol solution commonly used to clean the colon for colonoscopy. When the barcode on the jug of dialysis liquid did not scan, the nurse called the hospital pharmacy for assistance and was provided a new barcode via a tube system. After the patient had difficulty drinking the solution, the nurse gave the rest of the liquid through a feeding tube bag. The medication mix-up was identified around midnight and the patient died about 7 hours later. 

This Month’s Perspectives

Joan Stanley
Interview
Joan Stanley, PhD, NP, FAAN, FAANP |
Joan Stanley is the chief academic officer at the American Association of Colleges of Nursing (AACN).  We spoke to her about how undergraduate professional nursing education integrates the topic of patient safety into classroom and clinical instruction, and how this affects patient safety as a whole.
Perspectives on Safety
Joan Stanley, PhD, NP, FAAN, FAANP; Bryan M. Gale, MA; Sarah E. Mossburg, RN, PhD |
This piece discusses how undergraduate professional nursing education integrates the topic of patient safety into classroom and clinical instruction, and how this affects patient safety as a whole.
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