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Medication use evaluation of high-dose long-term opioid de-prescribing in multiple Veterans Affairs medical centers.

Barrett AK, Sandbrink F, Mardian A, et al. Medication use evaluation of high-dose long-term opioid de-prescribing in multiple Veterans Affairs medical centers. J Gen Intern Med. 2022;37(16):4037-4046. doi:10.1007/s11606-022-07807-8.

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January 18, 2023
Barrett AK, Sandbrink F, Mardian A, et al. J Gen Intern Med. 2022;37(16):4037-4046.
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Opioid medication use is associated with an increased risk of adverse events; however research has shown sudden discontinuation of opioids is also associated with adverse events such as withdrawal and hospitalization. This before and after study evaluated the impact of the VA’s Opioid Safety Initiative (OSI) on characteristics and prescribing practices. Results indicate that length of tapering period increased, and mortality risk decreased following OSI implementation.

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Barrett AK, Sandbrink F, Mardian A, et al. Medication use evaluation of high-dose long-term opioid de-prescribing in multiple Veterans Affairs medical centers. J Gen Intern Med. 2022;37(16):4037-4046. doi:10.1007/s11606-022-07807-8.