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Association of inappropriate outpatient pediatric antibiotic prescriptions with adverse drug events and health care expenditures.

Butler AM, Brown DS, Durkin MJ, et al. Association of inappropriate outpatient pediatric antibiotic prescriptions with adverse drug events and health care expenditures. JAMA Netw Open. 2022;5(5):e2214153. doi: 10.1001/jamanetworkopen.2022.14153

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June 8, 2022
Butler AM, Brown DS, Durkin MJ, et al. JAMA Netw Open. 2022;5(5):e2214153.

Inappropriately prescribing antibiotics for non-bacterial infections remains common in outpatient settings despite the associated risks. This analysis of antibiotics prescribed to more than 2.8 million children showed more than 30% of children with bacterial infection, and 4%-70% of children with viral infection were inappropriately prescribed antibiotics. Inappropriate prescribing led to increased risk of adverse drug events (e.g., allergic reaction) and increased health expenditures in the following 30 days.

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Butler AM, Brown DS, Durkin MJ, et al. Association of inappropriate outpatient pediatric antibiotic prescriptions with adverse drug events and health care expenditures. JAMA Netw Open. 2022;5(5):e2214153. doi: 10.1001/jamanetworkopen.2022.14153