Autopsies are integral to detection of major diagnostic errors (DE). In this study, 852 autopsies containing one or more DE were investigated for potential gender and/or racial bias. From 2012-2015, DE rates were higher for women compared to men, but no significant effect of race was observed. From 2015-2019, however, there were no significant differences by gender, but patients identified as non-white showed higher rates of DE.